The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization

Macrophages polarize into functionally distinct subtypes while responding to microenvironmental cues. The identity of proximal transcription factors (TFs) downstream from the polarization signals are known, but their activity is typically transient, failing to explain the long-term, stable epigenomi...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Daniel, Bence, Czimmerer, Zsolt, Halasz, Laszlo, Boto, Pal, Kolostyak, Zsuzsanna, Poliska, Szilard, Berger, Wilhelm K., Tzerpos, Petros, Nagy, Gergely, Horvath, Attila, Hajas, György, Cseh, Timea, Nagy, Aniko, Sauer, Sascha, Francois-Deleuze, Jean, Szatmari, Istvan, Bacsi, Attila, Nagy, Laszlo
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608752/
https://ncbi.nlm.nih.gov/pubmed/33060136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.343038.120
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