Retinoid X receptor suppresses a metastasis-promoting transcriptional program in myeloid cells via a ligand-insensitive mechanism

Retinoid X receptor (RXR) regulates several key functions in myeloid cells, including inflammatory responses, phagocytosis, chemokine secretion, and proangiogenic activity. Its importance, however, in tumor-associated myeloid cells is unknown. In this study, we demonstrate that deletion of RXR in my...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kiss, Mate, Czimmerer, Zsolt, Nagy, Gergely, Bieniasz-Krzywiec, Pawel, Ehling, Manuel, Pap, Attila, Poliska, Szilard, Boto, Pal, Tzerpos, Petros, Horvath, Attila, Kolostyak, Zsuzsanna, Daniel, Bence, Szatmari, Istvan, Mazzone, Massimiliano, Nagy, Laszlo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635866/
https://ncbi.nlm.nih.gov/pubmed/28923935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700785114
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