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The inactive Dnmt3b3 isoform preferentially enhances Dnmt3b-mediated DNA methylation
The de novo DNA methyltransferases Dnmt3a and Dnmt3b play crucial roles in developmental and cellular processes. Their enzymatic activities are stimulated by a regulatory protein Dnmt3L (Dnmt3-like) in vitro. However, genetic evidence indicates that Dnmt3L functions predominantly as a regulator of D...
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| Vydáno v: | Genes Dev |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7608744/ https://ncbi.nlm.nih.gov/pubmed/33004415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.341925.120 |
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