The PWWP Domain of Dnmt3a and Dnmt3b Is Required for Directing DNA Methylation to the Major Satellite Repeats at Pericentric Heterochromatin

Dnmt3a and Dnmt3b are responsible for the establishment of DNA methylation patterns during development. These proteins contain, in addition to a C-terminal catalytic domain, a unique N-terminal regulatory region that harbors conserved domains, including a PWWP domain. The PWWP domain, characterized...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Main Authors: Chen, Taiping, Tsujimoto, Naomi, Li, En
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2004
Assuntos:
DNA Dynamics and Chromosome Structure
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517890/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15456878/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.20.9048-9058.2004
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