The PWWP Domain of Dnmt3a and Dnmt3b Is Required for Directing DNA Methylation to the Major Satellite Repeats at Pericentric Heterochromatin

Dnmt3a and Dnmt3b are responsible for the establishment of DNA methylation patterns during development. These proteins contain, in addition to a C-terminal catalytic domain, a unique N-terminal regulatory region that harbors conserved domains, including a PWWP domain. The PWWP domain, characterized...

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Εκδόθηκε σε:	Mol Cell Biol
Κύριοι συγγραφείς:	Chen, Taiping, Tsujimoto, Naomi, Li, En
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Taylor & Francis 2004
Θέματα:	DNA Dynamics and Chromosome Structure
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15456878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.20.9048-9058.2004
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