The PWWP Domain of Dnmt3a and Dnmt3b Is Required for Directing DNA Methylation to the Major Satellite Repeats at Pericentric Heterochromatin

Dnmt3a and Dnmt3b are responsible for the establishment of DNA methylation patterns during development. These proteins contain, in addition to a C-terminal catalytic domain, a unique N-terminal regulatory region that harbors conserved domains, including a PWWP domain. The PWWP domain, characterized...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Chen, Taiping, Tsujimoto, Naomi, Li, En
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2004
Témata:	DNA Dynamics and Chromosome Structure
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15456878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.20.9048-9058.2004
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