Loading...
Targeting BCL-2 in B-cell malignancies and overcoming therapeutic resistance
Defects in apoptosis can promote tumorigenesis and impair responses of malignant B cells to chemotherapeutics. Members of the B-cell leukemia/lymphoma-2 (BCL-2) family of proteins are key regulators of the intrinsic, mitochondrial apoptotic pathway. Overexpression of antiapoptotic BCL-2 family prote...
Saved in:
| Published in: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group UK
2020
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7608616/ https://ncbi.nlm.nih.gov/pubmed/33139702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03144-y |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|