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BCL-2 as therapeutic target for hematological malignancies

Disruption of the physiologic balance between cell proliferation and cell death is an important step of cancer development. Increased resistance to apoptosis is a key oncogenic mechanism in several hematological malignancies and, in many cases, especially in lymphoid neoplasias, has been attributed...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Perini, Guilherme Fleury, Ribeiro, Glaciano Nogueira, Pinto Neto, Jorge Vaz, Campos, Laura Tojeiro, Hamerschlak, Nelson
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946445/
https://ncbi.nlm.nih.gov/pubmed/29747654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0608-2
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