Activation of autophagy during farnesyl pyrophosphate synthase inhibition is mediated through PI3K/AKT/mTOR signaling

OBJECTIVES: Autophagy is divided into three phases: autophagosome engulfment of intracellular organelles and proteins, autophagosome fusion with lysosomes, and autolysosome degradation. The farnesyl pyrophosphate synthase inhibitor ibandronate (IBAN) has in vivo cardioprotective properties, potentia...

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Detaylı Bibliyografya
Yayımlandı:J Int Med Res
Asıl Yazarlar: Han, Jie, Huang, Chaoyang, Jiang, Jiukun, Jiang, Dongmei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: SAGE Publications 2019
Konular:
Pre-Clinical Research Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7607048/
https://ncbi.nlm.nih.gov/pubmed/31884848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060519875371
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