PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis

Loss-of-function variants of protein tyrosine phosphatase non-receptor type 2 (PTPN2) enhance risk of inflammatory bowel disease and rheumatoid arthritis; however, whether the association between PTPN2 and autoimmune arthritis depends on gut inflammation is unknown. Here we demonstrate that inductio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Hsieh, Wan-Chen, Svensson, Mattias N.D., Zoccheddu, Martina, Tremblay, Michael L., Sakaguchi, Shimon, Stanford, Stephanie M., Bottini, Nunzio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605542/
https://ncbi.nlm.nih.gov/pubmed/33055428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.141868
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