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Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling
Schwannomas are tumors of the Schwann cells that cause chronic pain, numbness, and potentially life-threatening impairment of vital organs. Despite the identification of causative genes, including NF2 (Merlin), INI1/SMARCB1, and LZTR1, the exact molecular mechanism of schwannoma development is still...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7605536/ https://ncbi.nlm.nih.gov/pubmed/32960816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.141514 |
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