Ras/MAPK Modifier Loci Revealed by eQTL in Caenorhabditis elegans

The oncogenic Ras/MAPK pathway is evolutionarily conserved across metazoans. Yet, almost all our knowledge on this pathway comes from studies using single genetic backgrounds, whereas mutational effects can be highly background dependent. Therefore, we lack insight in the interplay between genetic b...

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Detalles Bibliográficos
Publicado en:G3 (Bethesda)
Autores principales: Sterken, Mark G., van Bemmelen van der Plaat, Linda, Riksen, Joost A. G., Rodriguez, Miriam, Schmid, Tobias, Hajnal, Alex, Kammenga, Jan E., Snoek, Basten L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592943/
https://ncbi.nlm.nih.gov/pubmed/28751501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.1120
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