Ras/MAPK Modifier Loci Revealed by eQTL in Caenorhabditis elegans

The oncogenic Ras/MAPK pathway is evolutionarily conserved across metazoans. Yet, almost all our knowledge on this pathway comes from studies using single genetic backgrounds, whereas mutational effects can be highly background dependent. Therefore, we lack insight in the interplay between genetic b...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:G3 (Bethesda)
Egile Nagusiak: Sterken, Mark G., van Bemmelen van der Plaat, Linda, Riksen, Joost A. G., Rodriguez, Miriam, Schmid, Tobias, Hajnal, Alex, Kammenga, Jan E., Snoek, Basten L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Genetics Society of America 2017
Gaiak:
Investigations
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592943/
https://ncbi.nlm.nih.gov/pubmed/28751501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.1120
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