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Ras/MAPK Modifier Loci Revealed by eQTL in Caenorhabditis elegans

The oncogenic Ras/MAPK pathway is evolutionarily conserved across metazoans. Yet, almost all our knowledge on this pathway comes from studies using single genetic backgrounds, whereas mutational effects can be highly background dependent. Therefore, we lack insight in the interplay between genetic b...

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書目詳細資料
發表在:G3 (Bethesda)
Main Authors: Sterken, Mark G., van Bemmelen van der Plaat, Linda, Riksen, Joost A. G., Rodriguez, Miriam, Schmid, Tobias, Hajnal, Alex, Kammenga, Jan E., Snoek, Basten L.
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592943/
https://ncbi.nlm.nih.gov/pubmed/28751501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.1120
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