Ras/MAPK Modifier Loci Revealed by eQTL in Caenorhabditis elegans

The oncogenic Ras/MAPK pathway is evolutionarily conserved across metazoans. Yet, almost all our knowledge on this pathway comes from studies using single genetic backgrounds, whereas mutational effects can be highly background dependent. Therefore, we lack insight in the interplay between genetic b...

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Dettagli Bibliografici
Pubblicato in:G3 (Bethesda)
Autori principali: Sterken, Mark G., van Bemmelen van der Plaat, Linda, Riksen, Joost A. G., Rodriguez, Miriam, Schmid, Tobias, Hajnal, Alex, Kammenga, Jan E., Snoek, Basten L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2017
Soggetti:
Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592943/
https://ncbi.nlm.nih.gov/pubmed/28751501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.1120
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