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Aging Uncouples Heritability and Expression-QTL in Caenorhabditis elegans

The number and distribution of gene expression QTL (eQTL) represent the genetic architecture of many complex traits, including common human diseases. We previously reported that the heritable eQTL patterns are highly dynamic with age in an N2 × CB4856 recombinant inbred population of the nematode Ca...

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Main Authors: Viñuela, Ana, Snoek, L. Basten, Riksen, Joost A. G., Kammenga, Jan E.
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362942/
https://ncbi.nlm.nih.gov/pubmed/22670229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.112.002212
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