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Aging Uncouples Heritability and Expression-QTL in Caenorhabditis elegans

The number and distribution of gene expression QTL (eQTL) represent the genetic architecture of many complex traits, including common human diseases. We previously reported that the heritable eQTL patterns are highly dynamic with age in an N2 × CB4856 recombinant inbred population of the nematode Ca...

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Bibliografiske detaljer
Main Authors: Viñuela, Ana, Snoek, L. Basten, Riksen, Joost A. G., Kammenga, Jan E.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362942/
https://ncbi.nlm.nih.gov/pubmed/22670229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.112.002212
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