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Aging Uncouples Heritability and Expression-QTL in Caenorhabditis elegans

The number and distribution of gene expression QTL (eQTL) represent the genetic architecture of many complex traits, including common human diseases. We previously reported that the heritable eQTL patterns are highly dynamic with age in an N2 × CB4856 recombinant inbred population of the nematode Ca...

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Bibliographische Detailangaben
Hauptverfasser: Viñuela, Ana, Snoek, L. Basten, Riksen, Joost A. G., Kammenga, Jan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362942/
https://ncbi.nlm.nih.gov/pubmed/22670229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.112.002212
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