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The RASopathies: Developmental syndromes of Ras/MAPK pathway dysregulation

The Ras/mitogen activated protein kinase (MAPK) pathway is essential in the regulation of the cell cycle, differentiation, growth and cell senescence, all of which are critical to normal development. It is therefore not surprising that its dysregulation has profound effects on development. A class o...

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Detalhes bibliográficos
Main Authors: Tidyman, William E., Rauen, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743116/
https://ncbi.nlm.nih.gov/pubmed/19467855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2009.04.001
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