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The RASopathies: Developmental syndromes of Ras/MAPK pathway dysregulation

The Ras/mitogen activated protein kinase (MAPK) pathway is essential in the regulation of the cell cycle, differentiation, growth and cell senescence, all of which are critical to normal development. It is therefore not surprising that its dysregulation has profound effects on development. A class o...

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Main Authors: Tidyman, William E., Rauen, Katherine A.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743116/
https://ncbi.nlm.nih.gov/pubmed/19467855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2009.04.001
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