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Expansion of the RASopathies
The Ras/mitogen activated protein kinase (MAPK) pathway is essential in the regulation of cell cycle, differentiation, growth, cell senescence and apoptosis, all of which are critical to normal development. A class of neurodevelopmental disorders, RASopathies, is caused by germline mutations in gene...
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Publicado no: | Curr Genet Med Rep |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5142630/ https://ncbi.nlm.nih.gov/pubmed/27942422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40142-016-0100-7 |
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