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The E3 ubiquitin ligase HECW1 targets thyroid transcription factor 1 (TTF1/NKX2.1) for its degradation in the ubiquitin-proteasome system

Thyroid transcription factor 1 (TTF1/NKX2.1), is a nuclear protein member of the NKX2 family of homeodomain transcription factors. It plays a critical role in regulation of multiple organ functions by promoting gene expression, such as thyroid hormone in thyroid and surfactant proteins in the lung....

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Liu, Jia, Dong, Su, Li, Lian, Wang, Heather, Zhao, Jing, Zhao, Yutong
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604857/
https://ncbi.nlm.nih.gov/pubmed/30849519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2019.03.005
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