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The E3 ubiquitin ligase CHIP mediates ubiquitination and proteasomal degradation of PRMT5
Protein arginine methyltransferase 5 (PRMT5) is an important member of the protein arginine methyltransferase family that regulates many cellular processes through epigenetic control of target gene expression. Because of its overexpression in a number of human cancers and its essential role in cell...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5397900/ https://ncbi.nlm.nih.gov/pubmed/26658161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2015.12.001 |
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