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The E3 ubiquitin ligase CHIP mediates ubiquitination and proteasomal degradation of PRMT5

Protein arginine methyltransferase 5 (PRMT5) is an important member of the protein arginine methyltransferase family that regulates many cellular processes through epigenetic control of target gene expression. Because of its overexpression in a number of human cancers and its essential role in cell...

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Bibliografski detalji
Izdano u:Biochim Biophys Acta
Glavni autori: Zhang, Huan-Tian, Zeng, Ling-Fei, He, Qing-Yu, Tao, W. Andy, Zha, Zhen-Gang, Hu, Chang-Deng
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397900/
https://ncbi.nlm.nih.gov/pubmed/26658161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2015.12.001
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