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Chylomicronemia from GPIHBP1 autoantibodies
Some cases of chylomicronemia are caused by autoantibodies against glycosylphosphatidylinositol-anchored HDL binding protein 1 (GPIHBP1), an endothelial cell protein that shuttles LPL to the capillary lumen. GPIHBP1 autoantibodies prevent binding and transport of LPL by GPIHBP1, thereby disrupting t...
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| 出版年: | J Lipid Res |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Biochemistry and Molecular Biology
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7604722/ https://ncbi.nlm.nih.gov/pubmed/32948662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R120001116 |
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