An ELISA for quantifying GPIHBP1 autoantibodies and making a diagnosis of the GPIHBP1 autoantibody syndrome

BACKGROUND: Autoantibodies against GPIHBP1, the endothelial cell transporter for lipoprotein lipase (LPL), cause severe hypertriglyceridemia (“GPIHBP1 autoantibodies syndrome”). Affected patients have low serum GPIHBP1 and LPL levels. We report the development of a sensitive and specific ELISA, suit...

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Publicat a:Clin Chim Acta
Autors principals: Miyashita, Kazuya, Fukamachi, Isamu, Machida, Tetsuo, Nakajima, Kiyomi, Young, Stephen, Murakami, Masami, Beigneux, Anne, Nakajima, Katsuyuki
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349362/
https://ncbi.nlm.nih.gov/pubmed/30287259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cca.2018.09.039
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