Lactate Induces Cisplatin Resistance in S. cerevisiae through a Rad4p-Dependent Process

Cisplatin is a widely used antineoplastic agent that has DNA as the main target, though cellular resistance hampers its therapeutic efficacy. An emerging hallmark of cancer cells is their altered metabolism, characterized by increased glycolysis even under aerobic conditions, with increased lactate...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Amaral, Leslie, Mendes, Filipa, Côrte-Real, Manuela, Sousa, Maria João, Chaves, Susana Rodrigues
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604607/
https://ncbi.nlm.nih.gov/pubmed/33163143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4971525
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky