Cisplatin cytotoxicity is dependent on mitochondrial respiration in Saccharomyces cerevisiae

OBJECTIVE(S): To understand the role of mitochondrial respiration in cisplatin sensitivity, we have employed wild-type and mitochondrial DNA depleted Rho0 yeast cells. MATERIALS AND METHODS: Wild type and Rho0 yeast cultured in fermentable and non-fermentable sugar containing media, were studied for...

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Bibliographic Details
Published in:Iran J Basic Med Sci
Main Authors: Inapurapu, Santhi priya, Kudle, Karunakar Rao, Bodiga, Sreedhar, Bodiga, Vijaya Lakshmi
Format: Artigo
Language:Inglês
Published: Mashhad University of Medical Sciences 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243979/
https://ncbi.nlm.nih.gov/pubmed/28133529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2017.8099
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