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Over-expression of COQ10 in Saccharomyces cerevisiae inhibits mitochondrial respiration

COQ10 deletion in Saccharomyces cerevisiae elicits a defect in mitochondrial respiration correctable by addition of coenzyme Q(2). Rescue of respiration by Q(2) is a characteristic of mutants blocked in coenzyme Q(6) synthesis. Unlike Q(6) deficient mutants, mitochondria of the coq10 null mutant hav...

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Main Authors: Zampol, Mariana A., Busso, Cleverson, Gomes, Fernando, Ferreira-Junior, Jose Ribamar, Tzagoloff, Alexander, Barros, Mario H.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175363/
https://ncbi.nlm.nih.gov/pubmed/20933507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.09.118
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