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Lactate Induces Cisplatin Resistance in S. cerevisiae through a Rad4p-Dependent Process
Cisplatin is a widely used antineoplastic agent that has DNA as the main target, though cellular resistance hampers its therapeutic efficacy. An emerging hallmark of cancer cells is their altered metabolism, characterized by increased glycolysis even under aerobic conditions, with increased lactate...
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| Publicado no: | Oxid Med Cell Longev |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7604607/ https://ncbi.nlm.nih.gov/pubmed/33163143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4971525 |
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