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Lactate Induces Cisplatin Resistance in S. cerevisiae through a Rad4p-Dependent Process
Cisplatin is a widely used antineoplastic agent that has DNA as the main target, though cellular resistance hampers its therapeutic efficacy. An emerging hallmark of cancer cells is their altered metabolism, characterized by increased glycolysis even under aerobic conditions, with increased lactate...
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| 出版年: | Oxid Med Cell Longev |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Hindawi
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7604607/ https://ncbi.nlm.nih.gov/pubmed/33163143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4971525 |
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