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p31(comet) promotes homologous recombination by inactivating REV7 through the TRIP13 ATPase
The repair of DNA double strand breaks (DSBs) that arise from external mutagenic agents and routine cellular processes is essential for life. DSBs are repaired by two major pathways, homologous recombination (HR) and classical nonhomologous end joining (C-NHEJ). DSB repair pathway choice is largely...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7604461/ https://ncbi.nlm.nih.gov/pubmed/33051298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008830117 |
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