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p31(comet) promotes homologous recombination by inactivating REV7 through the TRIP13 ATPase

The repair of DNA double strand breaks (DSBs) that arise from external mutagenic agents and routine cellular processes is essential for life. DSBs are repaired by two major pathways, homologous recombination (HR) and classical nonhomologous end joining (C-NHEJ). DSB repair pathway choice is largely...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sarangi, Prabha, Clairmont, Connor S., Galli, Lucas D., Moreau, Lisa A., D’Andrea, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604461/
https://ncbi.nlm.nih.gov/pubmed/33051298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008830117
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