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The NLRP3 inflammasome in macrophages is stimulated by cell‐free hemoglobin

Cell‐free hemoglobin (CFH) is associated with severe lung injury in human patients and is sufficient to induce airspace inflammation and alveolar–capillary barrier dysfunction in an experimental model of acute lung injury. The mechanisms through which this occurs are unknown. One key pathway which r...

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書目詳細資料
發表在:Physiol Rep
Main Authors: Shaver, Ciara M., Landstreet, Stuart R., Pugazenthi, Sangamithra, Scott, Fiona, Putz, Nathan, Ware, Lorraine B., Bastarache, Julie A.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601531/
https://ncbi.nlm.nih.gov/pubmed/33128438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14589
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