The NLRP3 inflammasome in macrophages is stimulated by cell‐free hemoglobin

Cell‐free hemoglobin (CFH) is associated with severe lung injury in human patients and is sufficient to induce airspace inflammation and alveolar–capillary barrier dysfunction in an experimental model of acute lung injury. The mechanisms through which this occurs are unknown. One key pathway which r...

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Bibliografski detalji
Izdano u:Physiol Rep
Glavni autori: Shaver, Ciara M., Landstreet, Stuart R., Pugazenthi, Sangamithra, Scott, Fiona, Putz, Nathan, Ware, Lorraine B., Bastarache, Julie A.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Original Researchs
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601531/
https://ncbi.nlm.nih.gov/pubmed/33128438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14589
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