Cell-free hemoglobin augments acute kidney injury during experimental sepsis

Acute kidney injury is a common complication of severe sepsis and contributes to high mortality. The molecular mechanisms of acute kidney injury during sepsis are not fully understood. Because hemoproteins, including myoglobin and hemoglobin, are known to mediate kidney injury during rhabdomyolysis,...

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Publicat a:Am J Physiol Renal Physiol
Autors principals: Shaver, Ciara M., Paul, Melinda G., Putz, Nathan D., Landstreet, Stuart R., Kuck, Jamie L., Scarfe, Lauren, Skrypnyk, Nataliya, Yang, Haichun, Harrison, Fiona E., de Caestecker, Mark P., Bastarache, Julie A., Ware, Lorraine B.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843044/
https://ncbi.nlm.nih.gov/pubmed/31364379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00375.2018
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