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Cell-free hemoglobin augments acute kidney injury during experimental sepsis

Acute kidney injury is a common complication of severe sepsis and contributes to high mortality. The molecular mechanisms of acute kidney injury during sepsis are not fully understood. Because hemoproteins, including myoglobin and hemoglobin, are known to mediate kidney injury during rhabdomyolysis,...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Shaver, Ciara M., Paul, Melinda G., Putz, Nathan D., Landstreet, Stuart R., Kuck, Jamie L., Scarfe, Lauren, Skrypnyk, Nataliya, Yang, Haichun, Harrison, Fiona E., de Caestecker, Mark P., Bastarache, Julie A., Ware, Lorraine B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843044/
https://ncbi.nlm.nih.gov/pubmed/31364379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00375.2018
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