Completing the Enalaprilat Excretion Pathway—Renal Handling by the Proximal Tubule

Background: Enalapril is often used in the treatment of cardiovascular diseases. Clinical data suggest that the urinary excretion of enalaprilat, the active metabolite of enalapril, is mediated by renal transporters. We aimed to identify enalaprilat specificity for renal proximal tubular transporter...

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Bibliografiske detaljer
Udgivet i:Pharmaceutics
Main Authors: Smeets, Nori J. L., Litjens, Carlijn H. C., van den Heuvel, Jeroen J. M. W., van Hove, Hedwig, van den Broek, Petra, Russel, Frans G. M., Koenderink, Jan B., de Wildt, Saskia N.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600309/
https://ncbi.nlm.nih.gov/pubmed/33007874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12100935
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