Dissecting G(q/11)-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1

Diverse extracellular signals induce plasma membrane translocation of sphingosine kinase-1 (SphK1), thereby enabling inside-out signaling of sphingosine-1-phosphate. We have shown before that G(q)-coupled receptors and constitutively active Gα(q/11) specifically induced a rapid and long-lasting SphK...

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Pubblicato in:Cells
Autori principali: Blankenbach, Kira Vanessa, Claas, Ralf Frederik, Aster, Natalie Judith, Spohner, Anna Katharina, Trautmann, Sandra, Ferreirós, Nerea, Black, Justin L., Tesmer, John J. G., Offermanns, Stefan, Wieland, Thomas, Meyer zu Heringdorf, Dagmar
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599897/
https://ncbi.nlm.nih.gov/pubmed/33003441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102201
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