The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection

Ebola virus (EBOV) is responsible for outbreaks with case fatality rates of up to 90% and for an epidemic in West Africa with more than ten thousand deaths. EBOV glycoprotein (EBOV-GP) is the only viral surface protein and is responsible for viral entry into cells. Here, by employing pseudotyped EBO...

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Vydáno v:iScience
Hlavní autoři: Imre, Gergely, Krähling, Verena, Eichler, Madeleine, Trautmann, Sandra, Ferreirós, Nerea, Aman, M. Javad, Kashanchi, Fatah, Rajalingam, Krishnaraj, Pöhlmann, Stefan, Becker, Stephan, Meyer zu Heringdorf, Dagmar, Pfeilschifter, Josef
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005759/
https://ncbi.nlm.nih.gov/pubmed/33817572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102266
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