A Sphingosine 1-Phosphate Gradient Is Linked to the Cerebral Recruitment of T Helper and Regulatory T Helper Cells during Acute Ischemic Stroke

Emerging evidence suggests a complex relationship between sphingosine 1-phosphate (S1P) signaling and stroke. Here, we show the kinetics of S1P in the acute phase of ischemic stroke and highlight accompanying changes in immune cells and S1P receptors (S1P(R)). Using a C57BL/6 mouse model of middle c...

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Опубликовано в: :Int J Mol Sci
Главные авторы: Lucaciu, Alexandra, Kuhn, Hannah, Trautmann, Sandra, Ferreirós, Nerea, Steinmetz, Helmuth, Pfeilschifter, Josef, Brunkhorst, Robert, Pfeilschifter, Waltraud, Subburayalu, Julien, Vutukuri, Rajkumar
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503682/
https://ncbi.nlm.nih.gov/pubmed/32872326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176242
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