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A Sphingosine 1-Phosphate Gradient Is Linked to the Cerebral Recruitment of T Helper and Regulatory T Helper Cells during Acute Ischemic Stroke

Emerging evidence suggests a complex relationship between sphingosine 1-phosphate (S1P) signaling and stroke. Here, we show the kinetics of S1P in the acute phase of ischemic stroke and highlight accompanying changes in immune cells and S1P receptors (S1P(R)). Using a C57BL/6 mouse model of middle c...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lucaciu, Alexandra, Kuhn, Hannah, Trautmann, Sandra, Ferreirós, Nerea, Steinmetz, Helmuth, Pfeilschifter, Josef, Brunkhorst, Robert, Pfeilschifter, Waltraud, Subburayalu, Julien, Vutukuri, Rajkumar
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503682/
https://ncbi.nlm.nih.gov/pubmed/32872326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176242
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