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Beta adrenoceptor blockade ameliorates impaired glucose tolerance and alterations of the cerebral ceramide metabolism in an experimental model of ischemic stroke

BACKGROUND: Sphingolipids are versatile signaling molecules derived from membrane lipids of eukaryotic cells. Ceramides regulate cellular processes such as proliferation, differentiation and apoptosis and are involved in cellular stress responses. Experimental evidence suggests a pivotal role of sph...

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Detalhes bibliográficos
Publicado no:Ther Adv Neurol Disord
Main Authors: Luger, Sebastian, Schwebler, Annette, Vutukuri, Rajkumar, Bouzas, Nerea Ferreiros, Labocha, Sandra, Schreiber, Yannick, Brunkhorst, Robert, Steinmetz, Helmuth, Pfeilschifter, Josef, Pfeilschifter, Waltraud
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949927/
https://ncbi.nlm.nih.gov/pubmed/29774054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756286418769830
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