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FTY720 Treatment in the Convalescence Period Improves Functional Recovery and Reduces Reactive Astrogliosis in Photothrombotic Stroke

BACKGROUND: The Sphingosine-1-phosphate (S1P) signaling pathway is known to influence pathophysiological processes within the brain and the synthetic S1P analog FTY720 has been shown to provide neuroprotection in experimental models of acute stroke. However, the effects of a manipulation of S1P sign...

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Detalhes bibliográficos
Main Authors: Brunkhorst, Robert, Kanaan, Nathalie, Koch, Alexander, Ferreirós, Nerea, Mirceska, Ana, Zeiner, Pia, Mittelbronn, Michel, Derouiche, Amin, Steinmetz, Helmuth, Foerch, Christian, Pfeilschifter, Josef, Pfeilschifter, Waltraud
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729514/
https://ncbi.nlm.nih.gov/pubmed/23936150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070124
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