FTY720 Treatment in the Convalescence Period Improves Functional Recovery and Reduces Reactive Astrogliosis in Photothrombotic Stroke

BACKGROUND: The Sphingosine-1-phosphate (S1P) signaling pathway is known to influence pathophysiological processes within the brain and the synthetic S1P analog FTY720 has been shown to provide neuroprotection in experimental models of acute stroke. However, the effects of a manipulation of S1P sign...

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Bibliografiske detaljer
Main Authors: Brunkhorst, Robert, Kanaan, Nathalie, Koch, Alexander, Ferreirós, Nerea, Mirceska, Ana, Zeiner, Pia, Mittelbronn, Michel, Derouiche, Amin, Steinmetz, Helmuth, Foerch, Christian, Pfeilschifter, Josef, Pfeilschifter, Waltraud
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729514/
https://ncbi.nlm.nih.gov/pubmed/23936150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070124
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