Coadministration of FTY720 and rt-PA in an experimental model of large hemispheric stroke–no influence on functional outcome and blood–brain barrier disruption

BACKGROUND: Systemic thrombolysis with recombinant tissue plasminogen activator (rt-PA) is the standard of acute stroke care. Its potential to increase the risk of secondary intracerebral hemorrhage, especially if administered late, has been ascribed to its proteolytic activity that has detrimental...

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Detalhes bibliográficos
Main Authors: Cai, Aijia, Schlunk, Frieder, Bohmann, Ferdinand, Kashefiolasl, Sepide, Brunkhorst, Robert, Foerch, Christian, Pfeilschifter, Waltraud
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029477/
https://ncbi.nlm.nih.gov/pubmed/24499647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-7378-5-11
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