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No Influence of Dabigatran Anticoagulation on Hemorrhagic Transformation in an Experimental Model of Ischemic Stroke

BACKGROUND: Dabigatran etexilate (DE) is a new oral direct thrombin inhibitor. Clinical trials point towards a favourable risk-to-benefit profile of DE compared to warfarin. In this study, we evaluated whether hemorrhagic transformation (HT) occurs after experimental stroke under DE treatment as we...

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Detalhes bibliográficos
Main Authors: Bohmann, Ferdinand, Mirceska, Ana, Pfeilschifter, Josef, Lindhoff-Last, Edelgard, Steinmetz, Helmuth, Foerch, Christian, Pfeilschifter, Waltraud
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404053/
https://ncbi.nlm.nih.gov/pubmed/22911709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040804
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