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Limiting homologous recombination at stalled replication forks is essential for cell viability: DNA2 to the rescue

The disease-associated nuclease–helicase DNA2 has been implicated in DNA end-resection during DNA double-strand break repair, Okazaki fragment processing, and the recovery of stalled DNA replication forks (RFs). Its role in Okazaki fragment processing has been proposed to explain why DNA2 is indispe...

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Detalhes bibliográficos
Publicado no:Curr Genet
Main Authors: Appanah, Rowin, Jones, David, Falquet, Benoît, Rass, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599155/
https://ncbi.nlm.nih.gov/pubmed/32909097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-020-01106-7
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