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Limiting homologous recombination at stalled replication forks is essential for cell viability: DNA2 to the rescue
The disease-associated nuclease–helicase DNA2 has been implicated in DNA end-resection during DNA double-strand break repair, Okazaki fragment processing, and the recovery of stalled DNA replication forks (RFs). Its role in Okazaki fragment processing has been proposed to explain why DNA2 is indispe...
Shranjeno v:
| izdano v: | Curr Genet |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer Berlin Heidelberg
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7599155/ https://ncbi.nlm.nih.gov/pubmed/32909097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-020-01106-7 |
| Oznake: |
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