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Limiting homologous recombination at stalled replication forks is essential for cell viability: DNA2 to the rescue
The disease-associated nuclease–helicase DNA2 has been implicated in DNA end-resection during DNA double-strand break repair, Okazaki fragment processing, and the recovery of stalled DNA replication forks (RFs). Its role in Okazaki fragment processing has been proposed to explain why DNA2 is indispe...
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| Yayımlandı: | Curr Genet |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Springer Berlin Heidelberg
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7599155/ https://ncbi.nlm.nih.gov/pubmed/32909097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-020-01106-7 |
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