T3 Critically Affects the Mhrt/Brg1 Axis to Regulate the Cardiac MHC Switch: Role of an Epigenetic Cross-Talk

The LncRNA my-heart (Mhrt) and the chromatin remodeler Brg1 inhibit each other to respectively prevent or favor the maladaptive α-myosin-heavy-chain (Myh6) to β-myosin-heavy-chain (Myh7) switch, so their balance crucially guides the outcome of cardiac remodeling under stress conditions. Even though...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Forini, Francesca, Nicolini, Giuseppina, Kusmic, Claudia, D’Aurizio, Romina, Mercatanti, Alberto, Iervasi, Giorgio, Pitto, Letizia
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598656/
https://ncbi.nlm.nih.gov/pubmed/32987653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102155
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker