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Integrative analysis of differentially expressed genes and miRNAs predicts complex T3-mediated protective circuits in a rat model of cardiac ischemia reperfusion

Thyroid hormone (T3) dyshomeostasis in the cardiac ischemia-reperfusion (IR) setting negatively impacts on mitochondria function and extracellular matrix remodeling. The modulation of cardiac miRNAs may represent the underlying molecular mechanisms, but a systems biology perspective investigating th...

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Forini, Francesca, Nicolini, Giuseppina, Kusmic, Claudia, D’Aurizio, Romina, Rizzo, Milena, Baumgart, Mario, Groth, Marco, Doccini, Stefano, Iervasi, Giorgio, Pitto, Letizia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138681/
https://ncbi.nlm.nih.gov/pubmed/30218079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32237-0
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