Early and Short-term Triiodothyronine Supplementation Prevents Adverse Postischemic Cardiac Remodeling: Role of Transforming Growth Factor-β1 and Antifibrotic miRNA Signaling

Activation of transforming growth factor (TGF)-β1 signaling in the ischemia/reperfusion (I/R) injured myocardium leads to dysregulation of miR-29-30-133, favoring the profibrotic process that leads to adverse cardiac remodeling (CR). We have previously shown that timely correction of the postischemi...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Nicolini, Giuseppina, Forini, Francesca, Kusmic, Claudia, Pitto, Letizia, Mariani, Laura, Iervasi, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: The Feinstein Institute Press 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818266/
https://ncbi.nlm.nih.gov/pubmed/26623926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00140
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