The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis

Psoriasis is a frequent, inflammatory skin disease characterized by keratinocyte hyperproliferation and a disease-related infiltration of immune cells. Here, we identified a novel proinflammatory signaling pathway driven by cyclin-dependent kinase 4 (CDK4) and CDK6 and the methyltransferase EZH2 as...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Müller, Anne, Dickmanns, Antje, Resch, Claudia, Schäkel, Knut, Hailfinger, Stephan, Dobbelstein, Matthias, Schulze-Osthoff, Klaus, Kramer, Daniela
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598068/
https://ncbi.nlm.nih.gov/pubmed/32701505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI134217
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker