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Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia

No treatment for frontotemporal dementia (FTD), the second most common type of early-onset dementia, is available, but therapeutics are being investigated to target the 2 main proteins associated with FTD pathological subtypes: TDP-43 (FTLD-TDP) and tau (FTLD-tau). Testing potential therapies in cli...

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Foilsithe in:J Clin Invest
Main Authors: Prudencio, Mercedes, Humphrey, Jack, Pickles, Sarah, Brown, Anna-Leigh, Hill, Sarah E., Kachergus, Jennifer M., Shi, J., Heckman, Michael G., Spiegel, Matthew R., Cook, Casey, Song, Yuping, Yue, Mei, Daughrity, Lillian M., Carlomagno, Yari, Jansen-West, Karen, de Castro, Cristhoper Fernandez, DeTure, Michael, Koga, Shunsuke, Wang, Ying-Chih, Sivakumar, Prasanth, Bodo, Cristian, Candalija, Ana, Talbot, Kevin, Selvaraj, Bhuvaneish T., Burr, Karen, Chandran, Siddharthan, Newcombe, Jia, Lashley, Tammaryn, Hubbard, Isabel, Catalano, Demetra, Kim, Duyang, Propp, Nadia, Fennessey, Samantha, Fagegaltier, Delphine, Phatnani, Hemali, Secrier, Maria, Fisher, Elizabeth M.C., Oskarsson, Björn, van Blitterswijk, Marka, Rademakers, Rosa, Graff-Radford, Neil R., Boeve, Bradley F., Knopman, David S., Petersen, Ronald C., Josephs, Keith A., Thompson, E. Aubrey, Raj, Towfique, Ward, Michael, Dickson, Dennis W., Gendron, Tania F., Fratta, Pietro, Petrucelli, Leonard
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598060/
https://ncbi.nlm.nih.gov/pubmed/32790644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI139741
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