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Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia

No treatment for frontotemporal dementia (FTD), the second most common type of early-onset dementia, is available, but therapeutics are being investigated to target the 2 main proteins associated with FTD pathological subtypes: TDP-43 (FTLD-TDP) and tau (FTLD-tau). Testing potential therapies in cli...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Prudencio, Mercedes, Humphrey, Jack, Pickles, Sarah, Brown, Anna-Leigh, Hill, Sarah E., Kachergus, Jennifer M., Shi, J., Heckman, Michael G., Spiegel, Matthew R., Cook, Casey, Song, Yuping, Yue, Mei, Daughrity, Lillian M., Carlomagno, Yari, Jansen-West, Karen, de Castro, Cristhoper Fernandez, DeTure, Michael, Koga, Shunsuke, Wang, Ying-Chih, Sivakumar, Prasanth, Bodo, Cristian, Candalija, Ana, Talbot, Kevin, Selvaraj, Bhuvaneish T., Burr, Karen, Chandran, Siddharthan, Newcombe, Jia, Lashley, Tammaryn, Hubbard, Isabel, Catalano, Demetra, Kim, Duyang, Propp, Nadia, Fennessey, Samantha, Fagegaltier, Delphine, Phatnani, Hemali, Secrier, Maria, Fisher, Elizabeth M.C., Oskarsson, Björn, van Blitterswijk, Marka, Rademakers, Rosa, Graff-Radford, Neil R., Boeve, Bradley F., Knopman, David S., Petersen, Ronald C., Josephs, Keith A., Thompson, E. Aubrey, Raj, Towfique, Ward, Michael, Dickson, Dennis W., Gendron, Tania F., Fratta, Pietro, Petrucelli, Leonard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598060/
https://ncbi.nlm.nih.gov/pubmed/32790644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI139741
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