Hypoxia-Inducible Factor alpha subunits regulate Tie2-expressing macrophages that influence tumor oxygen and perfusion in murine breast cancer

Tie2-expressing monocytes (TEMs) are a distinct subset of pro-angiogenic monocytes selectively recruited to tumors in breast cancer. Due to the hypoxic nature of solid tumors, we investigated if oxygen, via hypoxia inducible transcription factors HIF-1α and HIF-2α, regulates TEM function in the hypo...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Steinberger, Kayla J., Forget, Mary A., Bobko, Andrey A., Mihalik, Nicole E., Gencheva, Marieta, Roda, Julie M., Cole, Sara L., Mo, Xiaokui, Hoblitzell, E. Hannah, Evans, Randall, Gross, Amy C., Moldovan, Leni, Marsh, Clay B., Khramtsov, Valery V., Eubank, Timothy D.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596922/
https://ncbi.nlm.nih.gov/pubmed/32938724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000185
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars