Involvement of Tumor Macrophage HIFs in Chemotherapy Effectiveness: Mathematical Modeling of Oxygen, pH, and Glutathione

The four variables, hypoxia, acidity, high glutathione (GSH) concentration and fast reducing rate (redox) are distinct and varied characteristics of solid tumors compared to normal tissue. These parameters are among the most significant factors underlying the metabolism and physiology of solid tumor...

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Dades bibliogràfiques
Autors principals: Chen, Duan, Bobko, Andrey A., Gross, Amy C., Evans, Randall, Marsh, Clay B., Khramtsov, Valery V., Eubank, Timothy D., Friedman, Avner
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189793/
https://ncbi.nlm.nih.gov/pubmed/25295611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107511
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