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Hypoxia Inducible Factors-Mediated Inhibition of Cancer by GM-CSF: A Mathematical Model
Under hypoxia, tumor cells, and tumor-associated macrophages produce VEGF (vascular endothelial growth factor), a signaling molecule that induces angiogenesis. The same macrophages, when treated with GM-CSF (granulocyte/macrophage colony-stimulating factor), produce sVEGFR-1 (soluble VEGF receptor-1...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3936579/ https://ncbi.nlm.nih.gov/pubmed/23073704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11538-012-9776-3 |
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